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The study of hormone action requires the development of biosensors that allow fast and quantitative analysis of hormone levels. Here we describe new gibberellin biosensors that work well in plant protoplasts, in collaboration with Matías Zurbriggen (CEPLAS, Germany).
Posted on April 5th, 2024
Ratiometric gibberellin biosensors for the analysis of signaling dynamics and metabolism in plant protoplasts
Gibberellins regulate transcription through DELLA proteins. Here we show that one of the mechanisms relies on the ability of DELLAs to stabilize trancriptional complexes via their interaction with Mediator.
Posted on May 6th, 2024
DELLA proteins recruit the Mediator complex subunit MED15 to coactivate transcription in land plants

Our lab takes part on the Spanish network "EvoDevo SigNet". The kick-off meeting has taken place in Miraflores de la Sierra (Madrid) on April 11-12th.
Posted on April 12th, 2024
Spanish Network on the "Evolution of regulatory mechanisms in development and plant signaling"

SUMOylation is a critical modification that modulates the activity of proteins in all eukaryotes. In collaboration with Ari Sadanandom's group we have connected here the evolution of the SUMO system with developmental innovations in plants.
Posted on June 26th, 2024
Charting the evolutionary path of the SUMO modification system in plants reveals molecular hardwiring of development to stress adaptation

XVII Reunión de Biología Molecular de Plantas - Castellón de la Plana
A large representation of the lab has attended this year's Spanish Plant Molecular Biology Meeting in Castellón. We presented several posters, and Bruno's was selected for a short talk.
Posted on July 5th, 2024

XVII Reunión de Biología Molecular de Plantas - Castellón de la Plana
Our lab received the prize to the best scientific image in the XVII Spanish Meeting of Plant Molecular Biology. The image of RGA protein accumulation at the shoot apical meristem was taken by Antonio and artistically rendered by Mª Eugenia Blázquez.
Posted on July 10th, 2024

GIGANTEA adjusts the response to shade at dusk by directly impinging on PIF7 function
Plants respond differently to neighbour-imposed shade depending on the time of the day. We have now found a mechanism that explains this interaction between the circadian clock and the components of the shade response. Find here the details.
Posted on July 16th, 2024

Former members of the Plasticity Lab
The Vascular Development and TranslaTOM teams leave the umbrella of the Plasticity Lab. Find more info on their specific activities in their corresponding websites. We will still partner in several research projects.
Posted on July 31st, 2024
Light and temperature signals are integrated through a phyB-dependent gene regulatory network in rice
Arabidopsis phytochromes act as photoreceptors and thermosensors. They are the integral component of a small gene circuit that integrates light and temperature signals. In collaboration with Nelson Saibo's Lab in Lisbon, here we show that this integratory circuit is conserved in monocots too.
Posted on October 6th, 2024

Shade-induced ROS/NO reinforce COP1-mediated diffuse growth
It had been predicted that the lower photosynthetic activity under shade would generate lower levels of Reactive Oxygen Species. However we have found the opposite! Together with the Casal Lab, we propose that these ROS molecules help the plant adapt their growth under shade.
Posted on September 23rd, 2024

JAN
24
IBMCP Seminar
Our lab hosts Yka Helariutta (U. Helsinki)
JAN
31
Lab Meeting
Ana Marques

Several members of our lab have participated in the European Researchers' Night, explaining how plants interact with the environment and how they "measure" light and temperature. See more pictures here.
Posted on September 27th, 2024
Nit Europea de la Investigació
FEB
07
Lab Meeting
Santi
Characterisation of the R2T complex from Arabidopsis thaliana and its role in post-transcriptional regulation at high temperatures
Alberto Palacios has defended his PhD Thesis today, congratulations! We had Mar Castellano, Alejandro Ferrando and Emilio Gutiérrez-Beltrán as members of the PhD Committee. Check out more pictures here.
Posted on November 11th, 2024


Green Revolution DELLA Proteins: Functional Analysis and Regulatory Mechanisms
Our dear DELLA proteins are key regulatory elements that integrate environmental information into cellular responses. You can find here all you ever wanted to know about DELLAs and never dared to ask.
Posted on December 5th, 2024

Group's X-mas lunch at Fumiferro
Last group reunion in the year before the Christmas break. Some of our group members were missing, but the rest of us had lunch together right after the closing session of IBMCP's Annual Science Days.
Posted on December 19th, 2024
FEB
14
Lab Meeting
Maca
FEB
21
Lab Meeting
Carlos Gámez
FEB
28
Lab Meeting
Joaquín (2.11)
MAR
07
Lab Meeting
Rosa
MAR
14
Lab Meeting
Asier
MAR
21
Lab Meeting
Alexia - CANCELLED
MAR
28
Lab Meeting
Joan Candela
FEB
19
Department Seminar
Serrano Group - Nohales Group
MAR
12
Department Seminar
Carlos Gámez
APR
04
Lab Meeting
Pavel
APR
11
Lab Meeting
Clara
MAY
09
Lab Meeting
Damiano
MAY
16
Lab Meeting
Silvia

Divergent evolution of a thermospermine-dependent regulatory pathway in land plants
Evolution operates by shuffling the deck of cards. For example, we have discovered that the genetic circuit known to regulate vascular cell divisions in vascular plants is assembled in a completely different way in non-vascular plants, where it regulates entirely different processes. Learn more about it here.
Posted on January 9th, 2025
The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP
R2TP are cochaperones that help HSP90 to properly assemble essential cellular complexes. Despite the conservation across kingdoms, plant cochaperones have a distinct composition, and here we describe the CryoEM structure of the Arabidopsis cochaperone.
Posted on February 27th, 2025


PDRG1 is essential for early plant development as a component of the prefoldin-like complex
PDRG1 is an essential gene in all eukaryotes, but its mode of action is not understood. Here we show that it belongs to the Prefoldin-like complex in Arabidopsis and shares many functions with other known subunits. The photo shows PDRG1 expression in emerging lateral roots.
Posted on March 3rd, 2025
Hosting High School students in the lab
We have enjoyed the visit of Carla and Lucía, two students in Domus School (Godella, Valencia). They have spent three days in the lab getting acquainted with lab tasks and organization, and experiencing research activities.
Posted on March 14th, 2025

MAY
23
Lab Meeting
Paula
MAY
30
Lab Meeting
Joan Jordà
JUN
06
Lab Meeting
Victoria
JUN
13
Lab Meeting
Alba
APR
08-09
Lab Retreat
PIs of the Department of Development meet in Canet d'en Berenguer
JUN
02
EvoDevoSigNet Meeting
La Cristalera, Miraflores de la Sierra
Miguel will speak on:
"Evolution of multisensory integration during plant terrestrialization"